Sleeve gastrectomy is a bariatric surgery that involves removing a portion of the stomach, resulting in a smaller stomach size and reduced food intake. This surgery has been shown to have a significant effect on hunger hormones, leading to changes in appetite and food intake.
One of the primary hunger hormones affected by sleeve gastrectomy is ghrelin, also known as the “hunger hormone.” Ghrelin is produced in the stomach and stimulates appetite. Following sleeve gastrectomy, there is a decrease in ghrelin levels due to the removal of the portion of the stomach that produces the hormone. This reduction in ghrelin levels can lead to a decrease in appetite and food intake.
In addition to ghrelin, sleeve gastrectomy has been shown to have an effect on other hormones involved in appetite regulation, including leptin, insulin, and glucagon-like peptide-1 (GLP-1). Following sleeve gastrectomy, there is an increase in leptin levels, which can help regulate appetite and energy balance. Insulin sensitivity also improves, which can help with glucose regulation and weight loss. GLP-1, a hormone that promotes satiety and reduces food intake, is also increased after sleeve gastrectomy.
Overall, sleeve gastrectomy has a significant impact on hunger hormones, leading to changes in appetite and food intake that can contribute to weight loss and improved metabolic health. These hormonal changes play a critical role in the success of bariatric surgery in treating obesity and related metabolic disorders.